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March 2010

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Tue, 9 Mar 2010 20:26:17 -0500
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Thanks Denny, 
 
Found this which supports your comments but look at the levels  required... 
 
Toxicologic studies on borax and boric  acid  
 
 


References and further  reading may be available for this article. To view 
references and further  reading you must purchase this  article.





Robert J. Weir, Jr.   
Hazleton  Laboratories, Inc., Falls Church, Virginia, 22046, USA 

 
Russell S. Fisher Office of the Chief Medical Examiner  of the State of 
Maryland, Baltimore, Maryland 21201, USA
Received 22 July 1971.  
Available online 27 September  2004. 


In Sprague-Dawley rats the acute po LD50 values for borax were 4.5 g/kg and 
 4.98 g/kg in males and females. respectively; boric acid, 3.45 g/kg in 
males and  4.08 g/kg in females. In Long-Evans male rats the LD50 values for 
borax and  boric acid were 6.08 g/kg and 3.16 g/kg, respectively. In 90 day 
feeding  studies, rats tolerated both borax and boric acid at 525 ppm boron 
equivalent.  Dogs displayed no adverse effect at 175 ppm of borax (as boron 
equivalent) and  525 ppm of boric acid (as boron equivalent). In rats, high 
boron levels at 1750  and 5250 ppm of both compounds caused growth 
suppression, decreased food  utilization efficiency, degeneration of gonads and skin 
desquamation on the paws  and tails. At the 1750 ppm level, both boron 
compounds produced testicular  atrophy in all male dogs. Two year dietary feeding 
studies indicated that both  borax and boric acid could be tolerated by rats 
and dogs at 350 ppm boron  equivalent. Rats fed dietary boron compounds at 
1170 ppm levels showed toxic  signs which were found to be similar to those 
observed in subchronic studies.  Testicular degeneration was also observed in 
rats and dogs fed 1170 ppm levels.  Reproduction studies revealed that rats 
fed both borax and boric acid at 1170  ppm boron equivalent were sterile. 
Both compounds at 350 ppm boron equivalent  had no adverse effect on 
fertility, lactation, litter size, weight and  appearance.
 
So it goes...
 
Joe
 
 
 
 
In a message dated 3/9/2010 5:14:09 P.M. Pacific Standard Time,  
[log in to unmask] writes:

Yes, I know about all the "good" health applications of boric acid.  
However, in low doses, I it does not kill you, but damages the reproductive  
system - seems I read particularly males.  Soooooo, that makes it a  mutagen - 
and hence, "toxic".   Remember my rant a month ago that  started with "toxic 
computers".  Never mind that its lethal oral does is  comparable to table 
salt - as you point in your post.  Just remember the  three catagories of 
"toxic" now - 
 
 
•PBT  – Persistent,  Bioaccumulative,  and Toxic  
•CMR  – Carcinogenic,  Mutagenic,  or toxic for Reproduction  
•vPvB  – very  Persistent  and very  Bioaccumulative  















-----Original  Message-----
From: [log in to unmask]
To: [log in to unmask]
Sent: Tue,  Mar 9, 2010 7:02 pm
Subject: Re: [LF] More importantly.... 8 new substances  proposed for REACH 
control


_http://_www.stuffinanutshell.com/health/boricacid.html__ 
(http://www.stuffinanutshell.com/health/boricacid.html_)   
(_http://www.stuffinanutshell.com/health/boricacid.html_ 
(http://www.stuffinanutshell.com/health/boricacid.html) ) 
  
  
  
  
  
 In a message dated 3/9/2010 3:58:38 P.M. Pacific Standard Time,  
 [log in to unmask] (mailto:[log in to unmask])  writes:
 
 Thanks  Nigel.  
 
 Here in the US, the Aerospace Industries Association  EH&S committee sent 
 this around yesterday asking where these might be  used.  I am no expert 
in 
 fiberglass, but boric acid is listed as an  ingredient in E-Glass, that is 
 borosilicate glass.  I am not sure REACh  listing would cripple the supply 
of 
 boric acid as an intermeidate, but the  loss of E-glass in laminate would 
 probably be worse than the lead-free  issue.  Anyone on here a fiberglass 
 expert?  
 
 I think  fluoroborate plating is way down in board fab, but may not be 
 gone.   
 
 Any further impacts to report from the world of circuit  boards?
 
 Denny Fritz
 SAIC, Inc
 
 
 
 
 -----Original  Message-----
 From: Nigel Burtt <[log in to unmask] (mailto:[log in to unmask]) >
 To:  [log in to unmask] (mailto:[log in to unmask]) 
 Sent: Tue, Mar 9, 2010 4:16 pm
 Subject: [LF] More  importantly.... 8 new substances proposed for REACH 
 control
 
 
 The  eight substances suggested for consultation are:   
 Trichloroethylene
 Boric acid
 Disodium tetraborate,  anhydrous
 Tetraboron disodium heptaoxide, hydrate
 Sodium  chromate
 Potassium chromate
 Ammonium dichromate
 Potassium dichromate  
 See:  
 _http://echa.europa.eu/doc/press/pr_10_03_svhc_consultation_20100308.pdf_ 
(http://echa.europa.eu/doc/press/pr_10_03_svhc_consultation_20100308.pdf) 
 
 
 igel  Burtt
 NJAYBEE ASSOCIATES 
 EL: 44-8454-710989
 OBILE:  44-7941-232900
 KYPE: nigelburtt
 ww.nigelburtt.co.uk |  [log in to unmask] 
(mailto:[log in to unmask]) 
 
 
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