Joe,
Looks promising!
For those that don't know, Angewandte Chemie is one of the premiere chemistry journals.
Bev
RIM
----- Original Message -----
From: Leadfree <[log in to unmask]>
To: [log in to unmask] <[log in to unmask]>
Sent: Thu Jan 15 18:38:57 2009
Subject: [LF] NTC Possible new treatment for lead in blood plasma
While there has never been produced evidence of lead in electronic solder
causing harm to humans (excepting perhaps those in third world countries being
lured to recycle electronics using their cooking pots as it has been
suggested those exploited folks do... though numbers from scientific studies have not
yet been produced to my knowledge), it is nevertheless good to be able to
share the following bit of positive and promising news on the topic for those
who have not seen it.
Very best,
Joe
Magnetics nanoparticles carry toxic lead from blood
Jan. 15, 2009
Lead is one of the most dangerous heavy metals and is especially toxic to
children. Safe and effective detoxification processes are needed. As reported
in the journal Angewandte Chemie, a Korean team led by Won Seok Han and Jong
Hwa Jung has developed a new, highly promising approach. It is based on a
fluorescence receptor that selectively and strongly binds to lead ions. The
trick: the receptor is bound to magnetic nanoparticles and can be removed, along
with their lead cargo, in a simple hemodialysis procedure using magnets. By
using these magnetic particles, the researchers were able to remove 96 % of the
lead ions from blood samples mixed with lead in vitro.
Lead and lead salts are mainly ingested in foods or drinking water. Lead
pipes and lead-containing glazes on ceramic vessels are often a source of lead.
Usually, it is not acute lead poisoning that occurs, but rather gradual lead
poisoning, in which smaller amounts of the metal are accumulated over a long
period of time. Symptoms such as muscle weakness, disorientation, memory
loss, and anemia are the result. Currently, lead poisoning is treated with
chelation therapy, which has serious side effects: the chelates bind to other
minerals and trace elements as well as lead, removing these vital materials from
the body as well. Now an alternative is on the horizon.
The researchers’ idea starts with special probes used for the detection of
various specific metal ions, including lead. When a lead ion binds to such a “
lead receptor”, the receptor’s fluorescence is “switched on”, causing it to
glow. The receptor binds to no other metal ions, only lead. Perhaps a
selective lead detector could be used for detoxification, as well as detection. The
scientists synthesized a derivative of such a lead detector and also
equipped the molecule with a special chemical “anchor”.
They used this anchor to attach the receptor molecules to the surface of
magnetic nanoparticles made of silicon-dioxide-coated nickel.
Detoxification could theoretically work like hemodialysis: the blood is
diverted out of the body and into a special chamber containing the biocompatible
magnetic particles. By using magnetic fields, the charged magnetic particles
could be fished out. The purified blood is then reintroduced to the patient.
In contrast to chelation therapy, no vital minerals or trace elements would
be removed from the body in this process.
SOURCE: AZOM.com
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