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January 2009

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Subject:
From:
Joe Fjelstad <[log in to unmask]>
Reply To:
(Leadfree Electronics Assembly Forum)
Date:
Thu, 15 Jan 2009 18:38:57 EST
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While there has never been produced evidence of lead in  electronic solder 
causing harm to humans (excepting perhaps those in third world  countries being 
lured to recycle electronics using their cooking pots as it  has been 
suggested those exploited folks do... though numbers from  scientific studies have not 
yet been produced to my knowledge), it is  nevertheless good to be able to 
share the following bit of positive  and promising news on the topic for those 
who have not seen it. 
Very best, 
Joe 

Magnetics nanoparticles carry toxic lead from blood


Jan.  15, 2009

Lead is one of the most dangerous heavy metals and is  especially toxic to 
children. Safe and effective detoxification processes are  needed. As reported 
in the journal Angewandte Chemie, a Korean team led by Won  Seok Han and Jong 
Hwa Jung has developed a new, highly promising approach. It is  based on a 
fluorescence receptor that selectively and strongly binds to lead  ions. The 
trick: the receptor is bound to magnetic nanoparticles and can be  removed, along 
with their lead cargo, in a simple hemodialysis procedure using  magnets. By 
using these magnetic particles, the researchers were able to remove  96 % of the 
lead ions from blood samples mixed with lead in vitro.

Lead  and lead salts are mainly ingested in foods or drinking water. Lead 
pipes and  lead-containing glazes on ceramic vessels are often a source of lead. 
Usually,  it is not acute lead poisoning that occurs, but rather gradual lead 
poisoning,  in which smaller amounts of the metal are accumulated over a long 
period of  time. Symptoms such as muscle weakness, disorientation, memory 
loss, and anemia  are the result. Currently, lead poisoning is treated with 
chelation therapy,  which has serious side effects: the chelates bind to other 
minerals and trace  elements as well as lead, removing these vital materials from 
the body as well.  Now an alternative is on the horizon.

The researchers’ idea starts with  special probes used for the detection of 
various specific metal ions, including  lead. When a lead ion binds to such a “
lead receptor”, the receptor’s  fluorescence is “switched on”, causing it to 
glow. The receptor binds to no  other metal ions, only lead. Perhaps a 
selective lead detector could be used for  detoxification, as well as detection. The 
scientists synthesized a derivative of  such a lead detector and also 
equipped the molecule with a special chemical  “anchor”.

They used this anchor to attach the receptor molecules to the  surface of 
magnetic nanoparticles made of silicon-dioxide-coated  nickel.

Detoxification could theoretically work like hemodialysis: the  blood is 
diverted out of the body and into a special chamber containing the  biocompatible 
magnetic particles. By using magnetic fields, the charged magnetic  particles 
could be fished out. The purified blood is then reintroduced to the  patient. 
In contrast to chelation therapy, no vital minerals or trace elements  would 
be removed from the body in this process.

SOURCE:  AZOM.com
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