NC drills are highly versatile and stacking panels provides some economy  and
so it will be hard to displace them.

Punching can be fast (all holes at once) but is one at a time and depending
on approach, hole count and feature size the tooling might be costly and  must
be amortized over a number of panels to pay for the tool.

Hole quality is not as good making plating more of a challenge if you plan
on doing double sided PCBs. I have not heard of MLBs being punched  (except
when the drills got too dull ;-)

There should also be some concerned about punching small holes on fine  pitch
in glass fabric as there would be a higher risk of CAF, however  for polymer
films it is not so much of an issue.

I expect there will be other comments coming.

Joe

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