There is also a further complication in using GBL. If GBL is taken internally,
it is quickly converted to GHB (gamma hydroxybutyric acid), which is the Date
Rape Drug. Congress has passed a law (Public Law 106-172, passed on 2/18/2000,
"Hillory J. Farias and Samantha Reid Date-Rape Drug Prohibition Act of 2000'')
which will result in companies that manufacture, distribute, repackage, etc. GHB
to report on inventories of GHB, including GBL.
John Sharp, P.E.
Environmental & Safety Manager
Teradyne
Connection Systems Division
Nashua, NH 03062
Brian Ellis <[log in to unmask]> on 06/25/2000 10:19:08 AM
Please respond to "TechNet E-Mail Forum." <[log in to unmask]>; Please respond to
Brian Ellis <[log in to unmask]>
To: [log in to unmask]
cc: (bcc: John Sharp/NNH/Teradyne)
Subject: Re: [TN] SOLVENT's OCCUPATIONAL SAFETY
Jacob
I would treat this substance with great precaution. Firstly, it has a
cyclic epoxy group and is therefore probably somewhat reactive: it
probably has sufficient vapour pressure that respiration may be a
problem: it is an irritant to mucous membranes: in Europe it is classed
as a suspected carcinogen or mutagen and, if it is in an ink, it is
spread over great areas which will facilitate uncontrolled evaporation
in the workplace. Personally, I would leave well alone but, if in doubt,
call a qualified toxicologist and ask him to make a tox/epidemiological
literature search.
It is a sad reflection that chemicals that have not been fully
tox-researched can be used without restriction in industry, whereas more
benign molecules are often restricted. In the USA, OSHA will not seek a
full tox evaluation until there is a threat of large usage. A substance
is harmless until proved harmful, the complete antithesis to
pharmaceutical testing where a substance cannot be marketed until all
harmful side-effects are known. I know a cleaning solvent which is a
proven neurotoxic and reprotoxic on animals that is sold by the
thousands of tonnes per year into industry without restriction, without
an OSHA PEL/AEL and without any need for reporting!!!
Brian
JACOB MOZEL wrote:
>
>
> Hi,
>
> We would like to use an ink containing gamma-Butyro Lactone.
>
> I wonder if anyone has an idea if there is any problem as the
> occupational safety is concerned.
>
> Does anyone have experience of using any formulation containing this
> solvent.
>
> I have tried to make a decision based on the MSDS only, but we could
> reach an unanimous vote.
>
> Thanks
>
> Jacob Mozel
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