Thanks again, Denny
I found this sentence from the report to be the most entertaining...
"Thus, epidemiological studies in humans are insufficient to demonstrate
the
absence of an adverse effect on fertility." (Translation: "We would like
some more money, please")
Put another way they might have said instead... "the studies could not
prove an adverse effect on fertility"
Their wording reminds me a bit of the WMDs in Iraq.
Life on the other side of the looking glass is curious indeed ;-)
Joe
In a message dated 3/9/2010 5:53:23 P.M. Pacific Standard Time,
[log in to unmask] writes:
All - I have no problem with Joe's data. but here is what the EU (at the
recommendation of the Germans and Slovakians) is using. Read away - the
good parts about males is toward the end. ECHA is the European Chemicals
Agency.
_http://echa.europa.eu/doc/consultations/svhc/svhc_axvrep_germany_cmr_boric_
acid.pdf_
(http://echa.europa.eu/doc/consultations/svhc/svhc_axvrep_germany_cmr_boric_acid.pdf)
-----Original Message-----
From: [log in to unmask]
To: [log in to unmask]
Sent: Tue, Mar 9, 2010 8:26 pm
Subject: Re: [LF] More importantly.... 8 new substances proposed for REACH
control
Thanks Denny,
Found this which supports your comments but look at the levels
required...
Toxicologic studies on borax and boric acid
References and further reading may be available for this article. To view
references and further reading you must purchase this article.
Robert J. Weir, Jr.
Hazleton Laboratories, Inc., Falls Church, Virginia, 22046, USA
Russell S. Fisher Office of the Chief Medical Examiner of the State of
Maryland, Baltimore, Maryland 21201, USA
Received 22 July 1971.
Available online 27 September 2004.
In Sprague-Dawley rats the acute po LD50 values for borax were 4.5 g/kg
and
4.98 g/kg in males and females. respectively; boric acid, 3.45 g/kg in
males and 4.08 g/kg in females. In Long-Evans male rats the LD50 values
for
borax and boric acid were 6.08 g/kg and 3.16 g/kg, respectively. In 90
day
feeding studies, rats tolerated both borax and boric acid at 525 ppm
boron
equivalent. Dogs displayed no adverse effect at 175 ppm of borax (as
boron
equivalent) and 525 ppm of boric acid (as boron equivalent). In rats,
high
boron levels at 1750 and 5250 ppm of both compounds caused growth
suppression, decreased food utilization efficiency, degeneration of
gonads and
skin
desquamation on the paws and tails. At the 1750 ppm level, both boron
compounds produced testicular atrophy in all male dogs. Two year dietary
feeding
studies indicated that both borax and boric acid could be tolerated by
rats
and dogs at 350 ppm boron equivalent. Rats fed dietary boron compounds at
1170 ppm levels showed toxic signs which were found to be similar to
those
observed in subchronic studies. Testicular degeneration was also observed
in
rats and dogs fed 1170 ppm levels. Reproduction studies revealed that
rats
fed both borax and boric acid at 1170 ppm boron equivalent were sterile.
Both compounds at 350 ppm boron equivalent had no adverse effect on
fertility, lactation, litter size, weight and appearance.
So it goes...
Joe
In a message dated 3/9/2010 5:14:09 P.M. Pacific Standard Time,
[log in to unmask] (mailto:[log in to unmask]) writes:
Yes, I know about all the "good" health applications of boric acid.
However, in low doses, I it does not kill you, but damages the
reproductive
system - seems I read particularly males. Soooooo, that makes it a
mutagen -
and hence, "toxic". Remember my rant a month ago that started with
"toxic
computers". Never mind that its lethal oral does is comparable to table
salt - as you point in your post. Just remember the three catagories of
"toxic" now -
•PBT – Persistent, Bioaccumulative, and Toxic
•CMR – Carcinogenic, Mutagenic, or toxic for Reproduction
•vPvB – very Persistent and very Bioaccumulative
-----Original Message-----
From: [log in to unmask] (mailto:[log in to unmask])
To: [log in to unmask] (mailto:[log in to unmask])
Sent: Tue, Mar 9, 2010 7:02 pm
Subject: Re: [LF] More importantly.... 8 new substances proposed for
REACH
control
_http://_www.stuffinanutshell.com/health/boricacid.html__
(_http://www.stuffinanutshell.com/health/boricacid.html__
(http://www.stuffinanutshell.com/health/boricacid.html_) )
(_http://_www.stuffinanutshell.com/health/boricacid.html__
(http://www.stuffinanutshell.com/health/boricacid.html_)
(_http://www.stuffinanutshell.com/health/boricacid.html_
(http://www.stuffinanutshell.com/health/boricacid.html) ) )
In a message dated 3/9/2010 3:58:38 P.M. Pacific Standard Time,
[log in to unmask] (_mailto:[log in to unmask] (mailto:[log in to unmask]) )
writes:
Thanks Nigel.
Here in the US, the Aerospace Industries Association EH&S committee sent
this around yesterday asking where these might be used. I am no expert
in
fiberglass, but boric acid is listed as an ingredient in E-Glass, that
is
borosilicate glass. I am not sure REACh listing would cripple the
supply
of
boric acid as an intermeidate, but the loss of E-glass in laminate would
probably be worse than the lead-free issue. Anyone on here a fiberglass
expert?
I think fluoroborate plating is way down in board fab, but may not be
gone.
Any further impacts to report from the world of circuit boards?
Denny Fritz
SAIC, Inc
-----Original Message-----
From: Nigel Burtt <[log in to unmask] (_mailto:[log in to unmask]
(mailto:[log in to unmask]) ) >
To: [log in to unmask] (_mailto:[log in to unmask]
(mailto:[log in to unmask]) )
Sent: Tue, Mar 9, 2010 4:16 pm
Subject: [LF] More importantly.... 8 new substances proposed for REACH
control
The eight substances suggested for consultation are:
Trichloroethylene
Boric acid
Disodium tetraborate, anhydrous
Tetraboron disodium heptaoxide, hydrate
Sodium chromate
Potassium chromate
Ammonium dichromate
Potassium dichromate
See:
_http://echa.europa.eu/doc/press/pr_10_03_svhc_consultation_20100308.pdf_
(_http://echa.europa.eu/doc/press/pr_10_03_svhc_consultation_20100308.pdf_
(http://echa.europa.eu/doc/press/pr_10_03_svhc_consultation_20100308.pdf) )
igel Burtt
NJAYBEE ASSOCIATES
EL: 44-8454-710989
OBILE: 44-7941-232900
KYPE: nigelburtt
ww.nigelburtt.co.uk | [log in to unmask]
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